Ketamine dependence

The 2 types of Ketamine are injectable solution and powder or crystalline form. Enter your number below and one of the members of our admissions team will call you back shortly. Ketamine can disrupt the senses, judgment, and motor function for up to 24 hours after use.

What are the effects of ketamine?

Ketamine dependence

The biological factors that contribute to addiction are genes that affect dopamine regulation in the brain’s reward system. These factors include genetic predispositions, neurochemical changes, and alterations in brain function that make some individuals more vulnerable to dependency. For example, variations in genes like DRD2 affect dopamine receptors, making it harder for some people to Alcoholics Anonymous feel pleasure without external stimulation, leading to increased substance use. According to Morgan and Curran (2012), ketamine use can lead to lasting changes in brain function, increasing the risk of addiction over time.

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One case report suggested a glutamate release inhibitor called Lamotrigine to reduce ketamine cravings and depression, which are the most common problems reported by chronic ketamine users. Like other substance abuse treatments, behavioral therapies and support groups may provide further treatment assistance for ketamine addiction. To learn more about the treatment process, read our Ketamine rehabilitation guide, which provides ketamine addiction a comprehensive resource for starting this process. Ketamine is a schedule III controlled substance that is approved for medical use as a general anesthetic in procedures in human medicine.

What Are The Withdrawal Symptoms Of Ketamine Addiction?

Often, co-occurring disorders and polydrug use is also present, requiring a high level of care. Many inpatient rehabs offer treatment programs for ketamine addiction that can range from 28 days to several months. Symptoms typically set in between 24 to 72 hours after the last dose of ketamine.

Professional supervision is important to help individuals cope with both physical and psychological symptoms. Troches might also influence addiction risk because they are typically used more frequently than other forms of ketamine, such as infusions. The ease of access and self-administration increases the potential for misuse, especially if patients begin to crave the drug’s mood-enhancing effects. While not as fast-acting as other methods, regular use of ketamine in any form still leads to psychological dependence. Morgan and Curran (2012) noted that about 28% of recreational ketamine users reported symptoms of dependence, highlighting the risk even when the drug is taken as prescribed. Stopping use is an essential step for treating the physical and depressive symptoms and cognitive impairments caused by ketamine.

Ketamine dependence

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